If your base is the type with a separate mattress and adjustable base you can certainly replace the mattress.
Can any mattress go on an adjustable base.
Air bed mattresses that have adjustable pressure systems are becoming more popular and usually can be used on an adjustable base.
Soft medium or firm mattresses or even adjustable firmness mattresses can be chosen to sleep on when using the elevated bases.
No not all mattresses can pair with an adjustable bed frame.
Any firmness level mattress can be compatible with adjustable bed.
However the bending of an adjustable base can restrict the airflow in certain air bed mattresses which can cause the mattress to be too rigid to flex with ease.
The ones where the mattress and base are physically connected as one unit might be a little tricker to separate but not necessarily impossible.
Some types of mattresses offer the ability to change firmness.
Some beds with coils are too rigid to flex with the moving base and are therefore best kept on flat foundations instead.
Memory foam and hybrid.
And amedeo estimates that as many as half of the innerspring mattresses currently on the market would likely be compatible too.